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Because spermidine is not only obtained from the diet but is also endogenously synthesised and produced by the gut microbiota, the total polyamine pool reflects the combined contribution of all three sources, making it difficult to detect a shortage from any single source, and therefore true dietary depletion conditions are unlikely to occur 9

Cells expressing ABCC1 displayed significant resistance to thiosemicarbazones (Dp44mT, COTI-2, DpC) in both their metal-free and metal-bound forms

The advancement of 3D culture systems, including lung organoids and ALI models, has significantly improved COPD research by accurately mimicking the anatomy and physiology of HBE

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Carnitine is a powerful fat burner and energy booster