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Stress Reporter Assay of AQ-QI and DEAQ-QI To identify the stress response pathways upon AQ-QI and DEAQ-QI exposure, oxidative stress response (SRXN1-GFP), ER stress response (CHOP-GFP), inflammation response (ICAM1-GFP), and DNA damage response (p21-GFP) pathways were measured with a high-content image-based BAC-GFP stress responses reporter assay (Wink et al., 2014, 2017)

Chemical Reviews

Research involving this compound typically focuses on copper peptide signaling behavior, skin matrix pathway activity, collagen pathway research, extracellular matrix response, peptide-metal complex activity, cellular signaling, structure-function relationships, and measurable cellular response in experimental systems