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Moreover, Con A-injected mice also showed low GSH/GSSG ratio, increased hydrogen peroxide and high MDA level in the liver and spleen compared with Con A-injected WT mice (Figure 6)

The response to levodopa in Parkinsons disease: imposing pharmacological law and order

doi: 10.1038/clpt.2014.174 196

While the peak for GSH (2.98 min) gradually decreased, the signal corresponding to GSSG increased (4.37 min), indicative of the expected chemical transformation (Fig