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Back to Journals International Journal of Chronic Obstructive Pulmonary Disease Volume 12 MAPK/FoxA2-mediated cigarette smoke-induced squamous metaplasia of bronchial epithelial cells Authors Du C , Lu J, Zhou L, Wu B, Zhou F, Gu L, Xu D, Sun Y Received 5 June 2017 Accepted for publication 10 October 2017 Published 21 November 2017 Volume 2017:12 Pages 33413351 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Chunxue Bai Chunling Du,* Jinchang Lu,* Lei Zhou, Bo Wu, Feng Zhou, Liang Gu, Donghui Xu, Yingxin Sun Department of Respiratory Medicine, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China *These authors contributed equally to this work Objective: To explore the effect of cigarette smoke (CS) on the development of squamous metaplasia in human airway epithelial cells and the role of MAPK- and FoxA2-signaling pathways in the process

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And thats why people smoke