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They occur at the N- and C-terminal ends of histone proteins as well as in the globular region within the nucleosome core [8]

For the Live/Dead assays, macrophages in each well were treated with Se/LDH@PEG at different concentrations (25, 50, 100 and 200 g/mL) for 72 h, and then washed with PBS and incubated with Calcein/PI Reagent for 20 min, followed by imaged under a fluorescence microscope