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This method could confirm the stability of the target protein in a complex with the candidate ligands and determine the stability and rigidity of proteinligand complexes in a specific artificial environment, such as the body [32]

doi: 10.1093/aobpla/plv069 78 OchsR

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Modulating the tumor microenvironment with new therapeutic nanoparticles: a promising paradigm for tumor treatment

Binding of LTC 4 to its internalized receptors then sets in motion nuclear and perinuclear translocation of NOX4, generating ROS, oxidative nuclear DNA damage, apoptosis and necrosis