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Description

increase by ~50 g each week as tolerated

GH regulation involves a sophisticated feedback system

This dose-response consideration informs why research protocols rarely exceed the documented dose ranges

The results of these studies have been inconsistent and there appears to be a close interplay between GH treatment/exercise and sex steroid therapy on the improvement of muscle mass/strength in sarcopenia with most studies showing that one intervention alone is less likely to lead to increase in muscle mass/strength (Taaffe et al., 1994