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This non-surgical treatment is ideal for patients with a square or widened jaw who desire a more feminine or V-shaped facial profile

doi: 10.1007/s13555-018-0278-6 [DOI] [PMC free article] [PubMed] [Google Scholar] 79.Man AWC, Li H, Xia N

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While the transappendageal pathway, which utilizes appendages such as hair follicles, sweat ducts, and sebaceous glands, constitutes only about 0.1% of the skin surface area (though this percentage may be higher in specific regions such as the forehead) [22], its contribution to percutaneous transport is generally considered secondary