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P., Yang, C., Vazquez, A

One of the known sea cucumber Plesiocolochirus minutus was found to own 9Z, 9Z configured tetrahydroastaxanthin and which has been considered to be a metabolite of AST [70]

[7] Gu Z, Shi C, Li J, et al. Palbociclib-based high-throughput combination drug screening identifies synergistic therapeutic options in HPV-negative head and neck squamous cell carcinoma. BMC Med. 2022;20(1):175. Published 2022 May 12. doi:10.1186/s12916-022-02373-6(IF:8.775)

In vitro experiments starting from this experimental observation demonstrated that alterations of FLNA levels in primary cultured prolactinoma cells by gene silencing or overexpression resulted in corresponding modifications of DRD2 levels, demonstrating that these two events are causally related