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Leptin has a dual effect on insulin resistance and insulin sensitivity Under physiological conditions, leptin receptors demonstrate abundant expression throughout peripheral musculoskeletal tissues, where the interaction between leptin and its receptors enhances insulin sensitivity, promotes glucose utilization, stimulates lipolysis, and facilitates skeletal muscle growth [194, 209, 210]

Aloe-emodin demonstrates broad-spectrum anti-cancer activity against various tumor types, including prostate, breast, lung, colon, cervical cancer, melanoma, nasopharyngeal, liver, pancreatic cancers and glioblastoma [499,500,501,502,503,504,505,506,507,508,509,510]

A study of the contamination by ochratoxin a of green and roasted coffee beans

RNA Isolation and qRT-PCR RNA was extracted from PC cells using TRIzol reagent (Ambion, Life Technologies)

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