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In drawing on studies that extend from clinical epidemiology, through genetics, pharmacotherapy and animal models, to cell biology and biochemistry, we have aimed to provide a comprehensible and accessible narrative, although this comes at the expense of a fully comprehensive and systematic (and inevitably longer) analysis

-3 DPA Protected neurons from neuroinflammation by balancing microglia M1/M2 polarizations through inhibiting NF-B/MAPK p38 signaling and activating neuron-BDNF-PI3K/AKT Pathways

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If neurologic signs, perform magnetic resonance imaging (MRI) of the brain or computed tomography (CT) to rule out intracranial lesions, brain tumors or referral to a neurologist

Discussion The initial M