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doi: 10.3390/ijms23084429 13

The prevalence of its reduced form in cells is due to the activity of glutathione reductase, which is both constitutive and inducible in response to oxidative stress

To verify that the binding of the C-terminal region of ATG2A to the ER membrane can inhibit autophagy, we generated a mutant of ATG2A by incorporating an ER targeting sequence (Tiwari and Weissman, 2001