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So the first honest distinction is structural: tesamorelin is a modified full-length analog engineered for resistance to degradation, whereas sermorelin is an unmodified short fragment that reproduces GHRH activity but not GHRH stability

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Additionally, the brain needs to release more follicle stimulating hormone (FSH) to stimulate these abnormal eggs to mature and typically does so even in the luteal phase prior to the cycle being tracked, resulting in a shortened follicular phase and early ovulation