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Polycyclic aromatic hydrocarbons (PAH), many of which are carcinogenic, consist of three or more fused aromatic rings resulting from incomplete combustion of organic (carbonaceous) materials, and are often found in coal tar, soot, broiled foods, and automobile engine exhaust

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For example, PAHDNA adducts are observed in lung tissues, and p53 tumor suppressor mutations in lung tumors resemble the damage created by PAH diol epoxide metabolites in vitro

PMID 16880445

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