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New biologics and targeted therapies in SLE target a broad spectrum of key immune players, including B/T lymphocytes, plasmacytoid dendritic cells (pDC), plasma cells, T/B cell co-stimulation molecules, cytokines or their receptors, and various intracellular signaling pathways

J Cell Biol , accepted (2025)

Psychiatry Psychiatr Epidemiol

The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation

And since mitochondria within the cancer cell are responsible for not only generating energy but also providing metabolites, it is unsurprising that a handful of recent studies have linked mitochondrial activity to metastasis in breast, renal, and pancreatic cancers