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Stability of Pycnogenol as an ingredient in fruit juices subjected to in vitro gastrointestinal digestion

10.1007/s12161-021-02102-4 Food Anal

Iron metabolism critically intersects with oxidative stress pathways, as iron overload potentiates reactive oxygen species production via Fenton chemistry, which transforms H 2 O 2 into highly destructive hydroxyl radicals (OH) (77, 147, 148)

In the flow analysis with Annexin-V-PI double staining, PFOS increased early (lower right) and late (upper right) cell apoptosis by approximately 10%, which was substantially reduced to 2.8% through the administration of additional l-Carnitine pretreatment to RTCs at the 6-h point of their PFOS treatment (Fig

The UPR elicits both cytoprotective and cytotoxic signaling cascades, with the latter including cell death and inflammation [reviewed in (Iurlaro and Muoz-Pinedo, 2016)]