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[100] Cannabis smoking was common in the Middle East before the arrival of tobacco, and was early on a common social activity that centered around the type of water pipe called a hookah

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The peer-reviewed, two-part regression analysis is too complex to describe here in detail, and the technical discussion has been relegated to "Appendix A: The Econometric Analysis." In general terms, however, the model compares legal, per-capita sales of cigarettes to survey data on the percentage of smokers in each state (the survey data comes from the "Behavioral Risk Factor Surveillance System" administered by the Centers for Disease Control and Prevention)