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3,17 Less frequent phlebotomy therapy may be necessary in some patients who cannot tolerate weekly treatments

Kanbay M, Copur S, Ozbek L, Mutlu A, Cejka D, Ciceri P, Cozzolino M, Haarhaus ML (2024) Klotho: a potential therapeutic target in aging and neurodegeneration beyond chronic kidney disease-a comprehensive review from the ERA CKD-MBD working group

The skin-lightening effect remains as long as you continue the treatment

Each patient starts with a subcutaneous injection of a lower dose once a week for four weeks in the abdomen, upper arm, or thigh