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Supplementing preservation solution with mitochondria-targeted H2 S donor AP39 protects cardiac grafts from prolonged cold ischemia-reperfusion injury in heart transplantation

Decades of dismissal have left these conditions poorly understood, meaning over two thirds of R&D funding is being spent on basic research

Furthermore, the pharmacological induction of HSP expression with geranylgeranylacetone (GGA) is antiarrhythmic in both in vitro HL-1 cells and in vivo dogs, and oral GGA treatment has been shown to induce atrial HSP expression in humans undergoing cardiac surgery Figure 7

When in doubt, replace the vial