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Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

Additionally, catabolism occurs through cystathionine beta-synthase, leading to the formation of cystathioninea non-noxious product that further converts into cysteine

Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene

Crystal structures of the PARKIN1receptor (PDB code: 1MG8) [23], CREB (PDB code: 1KDX) [24], PINK (PDB code: 6EQI) [25], and TrkB receptor (PDB code: 5MO9) [26] were acquired from the RCSB Protein Data Bank ( [27]

In the present study, we focus on -OHB mainly because it is one of the most predominant ketone bodies in the ketogenic diet, accounting for 78% of the total number of plasma ketone bodies, and has a wide range of metabolic modulatory functions in both physiologic and pathologic states