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Enhancing protein folding and degradation processes, preventing cellular toxicity from misfolded proteins

The recommended dose of ALIMTA when administered with cisplatin for initial treatment of locally advanced or metastatic non-squamous NSCLC in patients with a creatinine clearance (calculated by Cockcroft-Gault equation) of 45 mL/min or greater is 500 mg/m2 as an intravenous infusion over 10 minutes administered prior to cisplatin on Day 1 of each 21-day cycle for up to six cycles in the absence of disease progression or unacceptable toxicity

Jozwiak Z, Jasnowska B

The nurses signature demonstrates accountability

doi: 10.1111/j.1471-4159.2006.03724.x