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The canonical Wnt pathway mainly controls cell proliferation, whereas the noncanonical Wnt pathways regulate cell polarity and migration, and the two main pathways form a network of mutual regulation

Aseptic technique, including swabbing the injection site with alcohol and using a fresh needle for each injection, is non-negotiable

Structurally, CAPS2 contains both a dynactin 1 interaction domain, suggesting that it may coordinate motor complex recruitment, and the Munc13-1 homologous domain, which is implicated in vesicle priming

More studies are also needed to evaluate the use of transcutaneous electrical nerve stimulation and manipulation (chiropractic and osteopathic) to treat lumbar spinal stenosis