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doi: 10.3389/fonc.2023.1193978 88 MiaomiaoSXiaoqianWYuweiSChaoCChenboYYinghaoLet al

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The relationship between NAM metabolism and NAD + utilization indicates that elevated NNMT expression may inhibit energy expenditure and promote fat deposition by limiting NAD + -dependent processes (Trammell and Brenner, 2015)