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The reliability test of the shoulder strength was done using test and retest method and the correlation coefficient ranged from 0.96 to 0.98

It is also characterized by iron overload and downregulated expression of anti-oxidant proteins, including glutathione peroxidases (GSH-Px), superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase 4 (GPX4)

These include cancer, neurodegenerative disorders, cardiovascular and metabolic syndromes, inflammatory conditions, and fibrotic diseases

reported that LC clinically decreases DNA damage in treated Maple syrup urine disease (MSUD) patients (44)

In this regard, precision geromedicine should take into account that the expression of metabolizing enzymes (such as cytochrome P450 isoforms) and hepatic membrane transporters are regulated, like many other genes, by clock-dependent mechanisms, and influence intestinal absorption, hepatic uptake, and biliary and renal excretion of various drugs (Zhang et al., 2009