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Description

For details on the underlying mechanisms, please refer to Supplementary Material 1

Tyrosine pathway A similar trend of a shift to noncanonical branches of tyrosine metabolism was also observed in this pathway

Wolpert et al

Gene 561, 7681

In both ESS mouse models and patients with pSS, tissue-specific CD8 + CD103 + CD69 + TRM was identified as being involved in sialadenitis, with a significant increase in IFN- production, in which CD69 and CD103 are the tissue residence markers (95)