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This system classifies substances by their potential to cause cancer (hazard) based on the strength of scientific evidence available

Am J Psychiatry 151:12341236 Jayaraman K, Das AK, Luethi D, Szollosi D, Schutz GJ, Reith MEA, Sitte HH, Stockner T (2021) SLC6 transporter oligomerization

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Normal mammalian cells, but mainly hepatocytes, adipocytes, macrophages, intestinal epithelial cells as well as endothelial and smooth muscle cells lining the blood vessels take up cholesterol from the blood by receptor-mediated endocytosis requiring of LDL binding to LDLR