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Gentamicin-induced nephrotoxicity triggers inflammation by activating the NF- transcription factor, which subsequently induces the production of pro-inflammatory cytokines IL-6 and TNF- 74,75 which in turn can exaggerate oxidative stress by producing more reactive oxygen species 32

It promotes healing by upregulating growth factors, stimulating angiogenesis (new blood vessel formation), and enhancing collagen synthesis

Intravitreal injections (IVIs) deliver drugs directly to the vitreous but necessitate frequent administration, hence increasing risks of endophthalmitis, retinal detachment, and patient non-compliance

11 , e2404753 (2024)

Large-scale analysis of gene expression, protein localization, and gene disruption in Saccharomyces cerevisiae