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Since it is well known that both ubiquitination and phosphorylation are involved in NRF2 regulation, it was no surprise that the acetylation of NRF2 also enhances its activity [214]

Unfortunately, all the four patients on trial treatment died of illness consistent with EVD (Sweiti et al., 2017)

Vitamin A, infection, and immune function

Moreover, the notable ability of NAC to suppress cancer cell proliferation and tumor growth suggests that targeting Notch2 may serve as a promising strategy for developing future therapies of GBM, implying a novel application of NAC on GBM therapy

The Perceived Stress Scale (PSS) (171) is a widely used 10-item scale assessing the degree of appraisal of life situations as unpredictable and beyond control causing additional burden to an individual