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Nat Rev Microbiol 22 , 155169 (2024)

With advancing age, the accumulation of toxins and the increasing damage from oxidative stress contribute to the development of a wide range of diseases and accelerate the ageing process

TXN/TXNRD1 inhibitors not only have anti-tumor activity, but also inhibit pulmonary fibrosis by inhibiting NF-B/TGF-1/Smads pathway [38]

An increase in tyrosine hydroxylase and dopamine transporter immunoreactivity in SNpc of PD mice was also observed after MP treatment

These free radicals are highly toxic and an exquisite fine control of how much and where in the cell they are generated is needed