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Coumarin , L-leucine , and 3-indolepropionic acid emerged as top-ranking features based on mean decrease in accuracy, indicating their relative importance as diet-responsive metabolites within this cohort

For instance, FAO accelerates the TCA cycle to produce citrate, which is exported to the cytosol to engage in NADPH production through ME1 and IDH1

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doi: 10.1016/j.clnu.2013.05.001 337 WangX.ValenzanoM

These changes were not due to the limitations of the Langendorff mouse heart model as we found comparable results on analysing in vivo ischaemia in the heart using the left anterior artery, descending (LAD) occlusion model (Supplementary Fig