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Front Pharmacol 9:15361561

Endemic nephropathy around the world

LDN has the ability to reduce pro-inflammatory cytokines as it was found to be allied with a decline of plasma concentrations of transforming growth factor (TGF)- which belongs to a group of cytokines that is together called The super-family TGF-, and also responsible for regulating epithelial cell differentiation, expansion , organization, motility, and apoptosis [98]