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Understanding the function of mammalian sirtuins and protein lysine acylation

Drug encapsulation is preferred as it has the potential to circumvent some in vivo limitations of therapeutic compounds such as rapid clearance, poor biodistribution, low plasma solubility and poor pharmacokinetics

10.1016/j.heliyon.2023.e17488 44 FaustinoC.DuarteN.PinheiroL

The transcription factors hypoxia-inducible factor (HIF)1 and HIF2 control the physiological response to hypoxia and invoke a program of increased erythropoiesis