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S.ChengH.KimS

Methods: We used the Vizient Clinical Database (VCD) to collect data on patients diagnosed with Hepatic Encephalopathy and Cirrhosis between 2019-2021

Mechanistically, SYVN1 binds to HMGB1, promoting its ubiquitination and degradation and alleviating SCIRI in rats by downregulating HMGB1 and activating the Nrf2/HO-1 pathway

Raised levels of homocysteine are also linked to Alzheimers, dementia, declining memory, poor concentration and judgment and lowered mood

Recently, our research group has identified the ferroptosis-related molecule SLC7A11 as playing a multifaceted role in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MASLD), influencing cystine levels and disease progression [141]